AAK1-KCMF1 Fusion FISH Probe
The AAK1-KCMF1 Fusion FISH Probe is used to confirm a fusion of the AAK1 and KCMF1 genes. The fusion of the AAK1 and KCMF1 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AAK1-KCMF1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| AAK1-KCMF1-20-RERE | 20 (40 μL) | 200 μL |
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| AAK1-KCMF1-20-REOR | 20 (40 μL) | 200 μL |
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| AAK1-KCMF1-20-REGO | 20 (40 μL) | 200 μL |
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| AAK1-KCMF1-20-REGR | 20 (40 μL) | 200 μL |
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| AAK1-KCMF1-20-REAQ | 20 (40 μL) | 200 μL |
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| AAK1-KCMF1-20-ORRE | 20 (40 μL) | 200 μL |
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| AAK1-KCMF1-20-OROR | 20 (40 μL) | 200 μL |
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| AAK1-KCMF1-20-ORGO | 20 (40 μL) | 200 μL |
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| AAK1-KCMF1-20-ORAQ | 20 (40 μL) | 200 μL |
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| AAK1-KCMF1-20-GORE | 20 (40 μL) | 200 μL |
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| AAK1-KCMF1-20-GOOR | 20 (40 μL) | 200 μL |
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| AAK1-KCMF1-20-GOGO | 20 (40 μL) | 200 μL |
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| AAK1-KCMF1-20-GOGR | 20 (40 μL) | 200 μL |
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| AAK1-KCMF1-20-GOAQ | 20 (40 μL) | 200 μL |
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| AAK1-KCMF1-20-GRRE | 20 (40 μL) | 200 μL |
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| AAK1-KCMF1-20-GROR | 20 (40 μL) | 200 μL |
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| AAK1-KCMF1-20-GRGO | 20 (40 μL) | 200 μL |
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| AAK1-KCMF1-20-GRGR | 20 (40 μL) | 200 μL |
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| AAK1-KCMF1-20-GRAQ | 20 (40 μL) | 200 μL |
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| AAK1-KCMF1-20-AQRE | 20 (40 μL) | 200 μL |
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| AAK1-KCMF1-20-AQOR | 20 (40 μL) | 200 μL |
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| AAK1-KCMF1-20-AQGO | 20 (40 μL) | 200 μL |
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| AAK1-KCMF1-20-AQGR | 20 (40 μL) | 200 μL |
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| AAK1-KCMF1-20-AQAQ | 20 (40 μL) | 200 μL |
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AAK1 Gene Summary
Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. This gene encodes a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Gene Name: AP2 Associated Kinase 1
Chromosome: CHR2: 69685126 -69870977
Locus: 2p13.3
KCMF1 Gene Summary
The Potassium Channel Modulatory Factor 1 (KCMF1) gene is located on chr2 :85198230-85286595 at 2p11.2.
Gene Name: Potassium Channel Modulatory Factor 1
Chromosome: CHR2: 85198230 -85286595
Locus: 2p11.2
Gene Diseases
The AAK1 KCMF1 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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