AAK1-C2ORF42 Fusion FISH Probe
The AAK1-C2ORF42 Fusion FISH Probe is used to confirm a fusion of the AAK1 and C2ORF42 genes. The fusion of the AAK1 and C2ORF42 genes has been associated with Ovarian Serous Cystadenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AAK1-C2ORF42-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| AAK1-C2ORF42-20-RERE | 20 (40 μL) | 200 μL |
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| AAK1-C2ORF42-20-REOR | 20 (40 μL) | 200 μL |
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| AAK1-C2ORF42-20-REGO | 20 (40 μL) | 200 μL |
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| AAK1-C2ORF42-20-REGR | 20 (40 μL) | 200 μL |
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| AAK1-C2ORF42-20-REAQ | 20 (40 μL) | 200 μL |
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| AAK1-C2ORF42-20-ORRE | 20 (40 μL) | 200 μL |
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| AAK1-C2ORF42-20-OROR | 20 (40 μL) | 200 μL |
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| AAK1-C2ORF42-20-ORGO | 20 (40 μL) | 200 μL |
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| AAK1-C2ORF42-20-ORAQ | 20 (40 μL) | 200 μL |
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| AAK1-C2ORF42-20-GORE | 20 (40 μL) | 200 μL |
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| AAK1-C2ORF42-20-GOOR | 20 (40 μL) | 200 μL |
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| AAK1-C2ORF42-20-GOGO | 20 (40 μL) | 200 μL |
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| AAK1-C2ORF42-20-GOGR | 20 (40 μL) | 200 μL |
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| AAK1-C2ORF42-20-GOAQ | 20 (40 μL) | 200 μL |
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| AAK1-C2ORF42-20-GRRE | 20 (40 μL) | 200 μL |
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| AAK1-C2ORF42-20-GROR | 20 (40 μL) | 200 μL |
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| AAK1-C2ORF42-20-GRGO | 20 (40 μL) | 200 μL |
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| AAK1-C2ORF42-20-GRGR | 20 (40 μL) | 200 μL |
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| AAK1-C2ORF42-20-GRAQ | 20 (40 μL) | 200 μL |
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| AAK1-C2ORF42-20-AQRE | 20 (40 μL) | 200 μL |
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| AAK1-C2ORF42-20-AQOR | 20 (40 μL) | 200 μL |
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| AAK1-C2ORF42-20-AQGO | 20 (40 μL) | 200 μL |
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| AAK1-C2ORF42-20-AQGR | 20 (40 μL) | 200 μL |
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| AAK1-C2ORF42-20-AQAQ | 20 (40 μL) | 200 μL |
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AAK1 Gene Summary
Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. This gene encodes a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Gene Name: AP2 Associated Kinase 1
Chromosome: CHR2: 69685126 -69870977
Locus: 2p13.3
C2orf42 Gene Summary
The Chromosome 2 Open Reading Frame 42 (C2orf42) gene is located on chr2 :70377016-70418151 at 2p13.3.
Gene Name: Chromosome 2 Open Reading Frame 42
Chromosome: CHR2: 70377016 -70418151
Locus: 2p13.3
Gene Diseases
The AAK1 C2ORF42 Fusion has been associated with the following diseases:
| Disease Name |
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| Ovarian Serous Cystadenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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