AACS-MAL Fusion FISH Probe
The AACS-MAL Fusion FISH Probe is used to confirm a fusion of the AACS and MAL genes. The fusion of the AACS and MAL genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AACS-MAL-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| AACS-MAL-20-RERE | 20 (40 μL) | 200 μL |
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| AACS-MAL-20-REOR | 20 (40 μL) | 200 μL |
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| AACS-MAL-20-REGO | 20 (40 μL) | 200 μL |
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| AACS-MAL-20-REGR | 20 (40 μL) | 200 μL |
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| AACS-MAL-20-REAQ | 20 (40 μL) | 200 μL |
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| AACS-MAL-20-ORRE | 20 (40 μL) | 200 μL |
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| AACS-MAL-20-OROR | 20 (40 μL) | 200 μL |
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| AACS-MAL-20-ORGO | 20 (40 μL) | 200 μL |
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| AACS-MAL-20-ORAQ | 20 (40 μL) | 200 μL |
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| AACS-MAL-20-GORE | 20 (40 μL) | 200 μL |
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| AACS-MAL-20-GOOR | 20 (40 μL) | 200 μL |
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| AACS-MAL-20-GOGO | 20 (40 μL) | 200 μL |
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| AACS-MAL-20-GOGR | 20 (40 μL) | 200 μL |
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| AACS-MAL-20-GOAQ | 20 (40 μL) | 200 μL |
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| AACS-MAL-20-GRRE | 20 (40 μL) | 200 μL |
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| AACS-MAL-20-GROR | 20 (40 μL) | 200 μL |
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| AACS-MAL-20-GRGO | 20 (40 μL) | 200 μL |
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| AACS-MAL-20-GRGR | 20 (40 μL) | 200 μL |
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| AACS-MAL-20-GRAQ | 20 (40 μL) | 200 μL |
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| AACS-MAL-20-AQRE | 20 (40 μL) | 200 μL |
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| AACS-MAL-20-AQOR | 20 (40 μL) | 200 μL |
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| AACS-MAL-20-AQGO | 20 (40 μL) | 200 μL |
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| AACS-MAL-20-AQGR | 20 (40 μL) | 200 μL |
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| AACS-MAL-20-AQAQ | 20 (40 μL) | 200 μL |
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MAL Gene Summary
The protein encoded by this gene is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids. The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction. In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and/or function. The protein plays a role in the formation, stabilization and maintenance of glycosphingolipid-enriched membrane microdomains. Down-regulation of this gene has been associated with a variety of human epithelial malignancies. Alternative splicing produces four transcript variants which vary from each other by the presence or absence of alternatively spliced exons 2 and 3. [provided by RefSeq, May 2012]
Gene Name: Mal, T-cell Differentiation Protein
Chromosome: CHR2: 95691478 -95719735
Locus: 2q11.1
AACS Gene Summary
The Acetoacetyl-CoA Synthetase (AACS) gene is located on chr12 :125549924-125627871 at 12q24.31.
Gene Name: Acetoacetyl-CoA Synthetase
Chromosome: CHR12: 125549924 -125627871
Locus: 12q24.31
Gene Diseases
The AACS MAL Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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