AACS-MAL Fusion FISH Probe

The AACS-MAL Fusion FISH Probe is used to confirm a fusion of the AACS and MAL genes. The fusion of the AACS and MAL genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads. Typical turnaround time for this product is 7-14 days after purchase.

AACS-MAL Fusion FISH Probe

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping

Download FISH ProtocolDownload Material Safety Data Sheet

SKU Test Kits Buffer Dye Color Order Now
AACS-MAL-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
AACS-MAL-20-RERE 20 (40 μL) 200 μL
AACS-MAL-20-REOR 20 (40 μL) 200 μL
AACS-MAL-20-REGO 20 (40 μL) 200 μL
AACS-MAL-20-REGR 20 (40 μL) 200 μL
AACS-MAL-20-REAQ 20 (40 μL) 200 μL
AACS-MAL-20-ORRE 20 (40 μL) 200 μL
AACS-MAL-20-OROR 20 (40 μL) 200 μL
AACS-MAL-20-ORGO 20 (40 μL) 200 μL
AACS-MAL-20-ORAQ 20 (40 μL) 200 μL
AACS-MAL-20-GORE 20 (40 μL) 200 μL
AACS-MAL-20-GOOR 20 (40 μL) 200 μL
AACS-MAL-20-GOGO 20 (40 μL) 200 μL
AACS-MAL-20-GOGR 20 (40 μL) 200 μL
AACS-MAL-20-GOAQ 20 (40 μL) 200 μL
AACS-MAL-20-GRRE 20 (40 μL) 200 μL
AACS-MAL-20-GROR 20 (40 μL) 200 μL
AACS-MAL-20-GRGO 20 (40 μL) 200 μL
AACS-MAL-20-GRGR 20 (40 μL) 200 μL
AACS-MAL-20-GRAQ 20 (40 μL) 200 μL
AACS-MAL-20-AQRE 20 (40 μL) 200 μL
AACS-MAL-20-AQOR 20 (40 μL) 200 μL
AACS-MAL-20-AQGO 20 (40 μL) 200 μL
AACS-MAL-20-AQGR 20 (40 μL) 200 μL
AACS-MAL-20-AQAQ 20 (40 μL) 200 μL

MAL Gene Summary

The protein encoded by this gene is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids. The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction. In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and/or function. The protein plays a role in the formation, stabilization and maintenance of glycosphingolipid-enriched membrane microdomains. Down-regulation of this gene has been associated with a variety of human epithelial malignancies. Alternative splicing produces four transcript variants which vary from each other by the presence or absence of alternatively spliced exons 2 and 3. [provided by RefSeq, May 2012]

Gene Name: Mal, T-cell Differentiation Protein

Chromosome: CHR2: 95691478 -95719735

Locus: 2q11.1

AACS Gene Summary

The Acetoacetyl-CoA Synthetase (AACS) gene is located on chr12 :125549924-125627871 at 12q24.31.

Gene Name: Acetoacetyl-CoA Synthetase

Chromosome: CHR12: 125549924 -125627871

Locus: 12q24.31

Gene Diseases

The AACS MAL Fusion has been associated with the following diseases:

Disease Name
Uterine Corpus Endometrial Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Scientific Citations

There are currently no FISH related citations for this gene.