Author Archives: Empire Genomics

Teagan’s Tech Tip: Avoiding the Most Common FFPE Pretreatment Mistakes

Teagan’s Tech Tip: Avoiding the Most Common FFPE Pretreatment Mistakes When it comes to FISH on FFPE tissue, pretreatment can make or break your results. Proper sample preparation helps ensure your probe can access its target while preserving the tissue morphology needed for confident analysis. In this edition of Teagan’s Tech Tip: Signal to Noise, […]

Teagan’s Tech Tip: 5 Quick Fixes for Better FISH Signal

Clear, bright FISH signals are only part of the equation. Reducing background noise is just as important for achieving results that are easy to visualize and interpret. If your signals are difficult to distinguish from the background, here are five areas to check before your next run. 1. Start With a Good Sample Foundation Whether you’re […]

Oncology FISH Probes

Clear signal. High specificity. Built for discovery and research insight. Empire Genomics Oncology FISH Probes are designed to support cancer research and molecular research workflows with strong, distinct signal quality and reproducible performance across a broad range of genomic targets. From solid tumors to hematologic malignancies, our oncology portfolio supports applications including gene amplification, deletion, […]

Teagan’s Tech Tip: Avoiding Hybridization Artifacts

Teagan’s Tech Tip: Avoiding Hybridization Artifacts Straight from the bench, our Field Application Scientist Teagan shares a few simple—but impactful—ways to reduce hybridization artifacts and improve signal-to-noise in your FISH workflow: Start with properly conditioned reagents Let your hybridization buffer fully equilibrate to room temperature before use. It’s more viscous than the probe concentrate, and […]

FFPE Slide Optimization Tips & Tricks

This webinar will walk you through protocol optimization of treatment and FISH for FFPE tissue samples, as well as provide troubleshooting tips and tricks for FFPE tissue processing. Upon completing the webinar, a technologist should have an in-depth knowledge of FFPE tissue treatment prior to FISH as well as an in-depth understanding of FISH for […]

Bone Marrow & Blood Protocol Optimization Tips

This episode of ‘Fishing with Ashlee’ will cover interphase FISH with blood and bone marrow samples. The benefits of interphase FISH with blood and bone marrow as well as a protocol for harvesting blood and bone marrow samples will be covered in depth. Images will be presented throughout the webinar to help a technician troubleshoot […]

FISH Troubleshooting 101

This episode of ‘Fishing with Ashlee’ will provide technologists with a plethora of images that depict common processing errors with FFPE tissue samples, blood and bone marrow samples, and other sample types used in FISH. The goal of this webinar is to expose technologists to images that correlate to specific problems in sample processing and […]

NTRK: Understanding Aberrations & Applications

Join our field application specialist Ashlee Dunne in our upcoming webinar on NTRK and its recent interest within the clinical and research community. During this webinar, attendees will learn more about the NTRK genes, their common fusion partners, and what one can expect to see in a normal or abnormal sample.