DermaFISH Quad Color FISH Probe

The DermaFISH Quad Color FISH Probe is a research-use-only (RUO) fluorescence in situ hybridization (FISH) assay designed for the visualization of genomic regions commonly studied in skin and cutaneous biology research. This quad-color probe enables simultaneous assessment of RREB1, MYB, and CCND1, along with a chromosome 6 centromere control (CEP6) within a single hybridization.

Each target is labeled with a distinct fluorophore, allowing researchers to efficiently examine copy number changes and chromosomal patterns across multiple loci in one experiment. The inclusion of the chromosome 6 centromere control provides a reference signal to support interpretation of gene-to-chromosome ratios during analysis.

The DermaFISH Quad Color FISH Probe is optimized for consistent hybridization performance and signal clarity in FFPE specimens, making it a reliable tool for exploratory, translational, and discovery-based research focused on cutaneous genomics, pigment cell biology, and chromosomal variation.

What genes does the DermaFISH™ Quad Color FISH Probe target?

• RREB1 – Ras-responsive element binding protein 1

• MYB – MYB proto-oncogene, transcription factor

• CCND1 – Cyclin D1

• CEP6 – Chromosome 6 centromere control