FISH Troubleshooting 101

This episode of ‘Fishing with Ashlee’ will provide technologists with a plethora of images that depict common processing errors with FFPE tissue samples, blood and bone marrow samples, and other sample types used in FISH. The goal of this webinar is to expose technologists to images that correlate to specific problems in sample processing and […]

NTRK: Understanding Aberrations & Applications

Join our field application specialist Ashlee Dunne in our upcoming webinar on NTRK and its recent interest within the clinical and research community. During this webinar, attendees will learn more about the NTRK genes, their common fusion partners, and what one can expect to see in a normal or abnormal sample.

Frequently Asked Questions About FISH Probes

In this webinar, attendees will learn the answers to some of our most commonly asked questions about probe and slide storage, slide making and processing, and analyzing FISH testing. A technologist who engages in the webinar should expect to leave with an understanding of proper storage of Empire Genomics probes, proper slide making and processing […]

Slide Washing

“Wash Away Your Probe-lems” addresses all things FISH washing. Upon completing the webinar, technologists should have an understanding of the importance of FISH washing, how to make and store proper wash solutions, and techniques involved in FISH washing. Technologists should also come from this webinar with washing tips that can be incorporated into their lab […]

Tips For Successful FISH Testing

This webinar will cover all the links in the process of successful FISH testing. A technologist should understand sample shipping and quality, mixture of reagents for FISH protocols, FISH protocol adjustments based on lab, equipment necessary for successful FISH testing, calibration and maintenance of the equipment, scope filters for probe dyes, and storage of FISHed […]

Empire Genomics Corp Awarded Molecular Agreement with Premier GPO!

Empire Genomics Corp Awarded Molecular Agreement with Premier GPO!

Buffalo, New York – April 1, 2024 – Empire Genomics Corp has been awarded a national group purchasing agreement for Molecular Analyzers, Reagents with Premier, Inc. Effective 02/01/2024, the new agreement allows Premier members, at their discretion, to take advantage of special pricing and terms pre-negotiated by Premier for FISH (Fluorescent in situ Hybridization) Probes. “Empire […]

Extrachromosomal MET Amplification Spurs Drug Resistance in ROS1+ NSCLC

Non-small-cell lung cancer (NSCLC) is a genetically heterogeneous disease. In approximately 2% of NSCLC cases, the primary oncogenic mutation is a chromosomal rearrangement involving ROS1 (ROS proto-oncogene 1), where one of many diverse gene partners fuses to the 3’ kinase domain of ROS1 and results in the constitutive activation of the ROS1 receptor tyrosine kinase. The ROS1-targeted tyrosine kinase inhibitor (TKI) entrectinib is an FDA-approved treatment for patients with these ROS1 fusions (ROS1+ NSCLC) and has dramatically improved patient outcomes.

Known Cancer Driver Mutations Found in Endometrial Polyps at Low Allelic Frequencies

Endometrial polyps (EMPs) are localized overgrowths of endometrial tissue composed of endometrial glands, stroma, and blood vessels. The reported prevalence of EMPs increases with age and ranges from 8-35%, depending on the population studied. EMPs are considered benign, with a risk of malignancy of around 3%.

Cerebrovascular β-Amyloid Deposits Linked to Altered Gene Expression Profile in Mice with Alzheimer’s Disease

Alzheimer’s disease (AD) is the most common form of dementia in older adults. Cerebral amyloid angiopathy (CAA), which is characterized by the deposition of β-amyloid (Aβ) peptides within cerebral blood vessels, co-occurs with AD to some extent in 85-95% of AD cases and is an independent contributor to AD dementia. Indeed, cerebrovascular dysfunction, possibly resulting from Aβ deposits, has been implicated in early AD pathogenesis, preceding neuronal damage.