Fully Automated Slide Stainer
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Pro Performance For Your Laboratory
The ONCORE Pro™ Automated Slide Staining System performs fully automated FISH, enabling streamlined processing of hematology and urine FISH probes with the convenience of a compact benchtop system.
The in vitro diagnostic (IVD)-labeled ONCORE Pro Automated Slide Staining System is a compact powerhouse for any clinical laboratory. ONCORE Pro opens a world of possibilities to perform FISH testing on a single streamlined platform. The system processes up to 36 slides in a single run, with the ability to perform independent protocols at each slide position for high-throughput slide processing.

This stainer’s slide processing is facilitated by unique reaction modules that enclose slides between a heated platform and a novel reagent containment chamber. Reagents are dispensed onto slides through a port attached to each chamber, allowing for minimal reagent usage and waste production. These unique chambers provide gentle agitation to enhance incubation throughout the hybridization procedure, maximizing signal intensity while minimizing background.
ONCORE Pro is a fully automated slide stainer utilizing advanced online pretreatment technology and pre-optimized protocols to enhance laboratory workflow, increase efficiency, and reduce hands-on processing time. Solve modern-day challenges facing your lab now and in the future with the advanced automated FISH staining system—ONCORE Pro.
- Fully Automated Online Antigen Retrieval (HIER)
- Ready to Use Single, Dual, Tri, & Quad Color Probes
- Conserve Bench Space with Compact Footprint
- Intuitive Software for Ease of Use & Protocol Programming
- 2-D Matrix Labels Virtually Eliminate Patient ID Errors
- Waste Separation Reduces Hazardous Waste & Disposal Costs

High-Throughput Capacity
ONCORE Pro benchtop platform expands the possibilities of your laboratory by performing Hematology and Urine FISH
Ultimate Flexibility Meets Advanced Productivity
Complete Automation
Our clinical slide stainer is a compact, bench-top instrument designed to automate in situ hybridization (ISH) procedures, including FISH, on blood, bone marrow & urine samples. The system offers fully integrated capabilities such as slide baking, deparaffinization, probe hybridization, post-hybridization washes, and counterstaining—all in a single run. With streamlined automation and precise temperature control, it ensures consistent, high-quality FISH results while reducing manual workload and variability.
Convenient & Easy to Use
ONCORE Pro X contains multiple features for added convenience, flexibility, and ease of use. The system’s software interface is intuitive and easy to use, requiring minimal user interaction from the beginning-to-end of a run. ONCORE Pro X also utilizes 2-D Matrix labels that can be printed for patient slides, significantly reducing patient identification errors. Independent slide positions allow for unique protocols to be performed on individual slides during a run.
Innovative Technologies
ONCORE Pro X utilizes unique reaction modules that protect slides between a heated platform and a reagent containment chamber. These chambers provide gentle agitation during reagent incubation to maximize stain intensity. Reagent vials are identified using RFID technology which stores vital information including name, lot number, expiration date, and the number of tests minimizing user error through real-time tracking of reagent volumes.
Ready to Use Reagents
Empire Genomics’ ready-to-use FISH reagents are specifically formulated for the ONCORE Pro™ system, delivering consistent and high-quality results across hematology and cytogenetic applications. These reagents are optimized for automation, eliminating the need for manual preparation and reducing variability between runs. Designed to integrate seamlessly with Empire’s ONCORE Pro™-formatted FISH probes, the system supports a wide range of sample types while improving workflow efficiency. Automating FISH with ONCORE Pro™ helps conserve technologist time, reduce slide handling, and streamline high-throughput testing environments.

System specifications
Slide Capacity |
36 slides |
Reagent Rack |
One reagent rack holds a maximum of 40 reagent vials |
Antigen Retrieval Temperature Range |
Room temperature to 103°C; Max 110°C at Sea Level |
Multi-Dispensing Syringe Capacity |
5mL |
Dispense Volume |
Antibody: 130uL; Reagent: 65 minimum – 400 μl maximum |
DePar Dispense Volume |
DS1 – 240uL and DS2 – 200uL |
Carboys & Waste |
Wash Buffer (2L), Hazardous (4L) and Non-Hazardous Waste (4L) |
Unit Control |
One Instrument Per Computer |
Instrument Weight |
125lbs (57 kgs) |
Instrument Dimensions |
36.5 in x 22 in x 24 in / 93 cm x 56 cm x 61 cm (Door Closed) 36.5 in x 36 in x 24 in / 93 cm x 91 cm x 61 cm (Door Open) |
Electrical Requirements |
120V 110/120V (±10%) 60Hz (±2Hz) 850 watts 220V 220/240V (±10%) 50Hz (±2Hz) 850 watts |
Voltage Tolerance |
100 to 240 AC |
Noise Rating |
Minimum Operating Noise 47.0 dBA, Maximum Operating Noise 69.6 dBA |
Reports |
Slide Barcode, Patient Information, Staining Runs |
LIS |
HL7 Server Connection and MSSQL Database Connection |
Learn More About ONCORE Pro
Submit your information and an Empire representative will be in touch with more details about ONCORE Pro.