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NISH Probes

Ready-to-use RNA-ISH Probes for NeoPATH Pro

NeoPATH Pro instrument
17+
Ready-to-Use Probes
2
Chromogen Options
5.5hr
Minimum Run Time

Powered by HCR™ Pro

Streamline Your Lab with The NISH Probe Portfolio.

The NISH Probe Portfolio is a library of ready-to-use RNA-ISH research probes for the NeoPATH Pro automated staining platform. Built on HCR™ Pro chemistry and HCR™ HiFi Probes, each assay uses patented background-suppressing probe design to deliver clear, specific signal at the target site — no protease digestion required.

Every probe is developed specifically for the NeoPATH Pro workflow, running alongside IHC, FISH, and chromogenic ISH on a single platform. The portfolio spans viral RNA, immunoglobulin light chains, and a growing menu of research targets to support gene expression mapping, biomarker characterization, and target validation.

Why NISH on NeoPATH Pro

5.5-hour turnaround — same-day results, fully automated from start to finish
HCR™ HiFi Probes deliver high specificity and low background with single-step amplification
Available in DAB or Fast Red chromogen — supports single-target and multiplex RNA-ISH panels
No protease digestion required — simplified sample prep optimized for diverse FFPE tissue types
Run ISH, IHC, and FISH on the same platform — one instrument for your full workflow
RUO
For in Vitro Research Use Only. Not for use in Diagnostic Procedures.

NISH - HPV Probes

Probe
Catalog #
Chemistry
Regulatory
Pack
NISHNISH HPV High Risk Probe
HPV-HR-20-R-NP
DABFast Red
RUO
20 Test
NISHNISH HPV Low Risk Probe
HPV-LR-20-R-NP
DABFast Red
RUO
20 Test
NISHNISH HPV 6/11 Probe
HPV6-HPV11-20-R-NP
DABFast Red
RUO
20 Test
NISHNISH HPV 16/18 Probe
HPV16-HPV18-20-R-NP
DABFast Red
RUO
20 Test
NISHNISH HPV 31/45 Probe
HPV31-HPV45-20-R-NP
DABFast Red
RUO
20 Test
NISHNISH HPV 6 Probe
HPV6-20-R-NP
DABFast Red
RUO
20 Test
NISHNISH HPV 11 Probe
HPV11-20-R-NP
DABFast Red
RUO
20 Test
NISHNISH HPV 16 Probe
HPV16-20-R-NP
DABFast Red
RUO
20 Test
NISHNISH HPV 18 Probe
HPV18-20-R-NP
DABFast Red
RUO
20 Test

NISH - ISH Probes

Probe
Catalog #
Chemistry
Regulatory
Pack
NISHNISH KAPPA Light Chain Probe
KAPPA-20-R-NP
DABFast Red
RUO
20 Test
NISHNISH LAMBDA Light Chain Probe
LAMBDA-20-R-NP
DABFast Red
RUO
20 Test
NISHNISH EBER Probe
EBER-20-R-NP
DABFast Red
RUO
20 Test
NISHNISH CMV Probe
CMV-20-R-NP
DABFast Red
RUO
20 Test
NISHNISH ERBB2 Probe
ERBB2-20-R-NP
DABFast Red
RUO
20 Test
NISHNISH ALBUMIN Probe
ALBUMIN-20-R-NP
DABFast Red
RUO
20 Test

NISH - Control Probes

Probe
Catalog #
Chemistry
Regulatory
Pack
NISHNISH Negative Control Probe
NNC-20-R-NP
DABFast Red
RUO
20 Test
NISHNISH Positive Control Probe
NPC-20-R-NP
DABFast Red
RUO
20 Test

Bring the NISH Portfolio to Your Lab Bench.

Speak with an ISH specialist about automating your ISH workflows or Scheduling a NeoPATH Pro Demonstration.

Talk to a Specialist Book a Demo