ONCORE Pro Wash Buffer

ONCORE Pro Wash Buffer is a ready-to-use Tris-buffered solution specifically formulated for FISH workflows on cytology and hematology specimens. Designed for use with the ONCORE Pro® Automated Slide Stainer, this buffer supports consistent, high-quality staining by thoroughly rinsing slides between each step of the hybridization and wash process.

Throughout FISH staining, each reagent must be removed completely before the next is applied to avoid cross-contamination or residual signal. This Wash Buffer performs reliable, efficient rinsing of both cytology and hematology slide preparations, helping reduce background fluorescence and improve signal clarity.

In addition, the buffer’s pH-balanced Tris formulation (pH 7.6–7.8) includes a surfactant for improved spread and a preservative that protects against microbial growth. These properties help ensure even reagent distribution, better probe performance, and cleaner slides across multiple runs.

Furthermore, the ONCORE Pro Wash Buffer ready-to-use format eliminates the need for dilution or preparation, reducing variability and saving valuable lab time. When incorporated into a standardized protocol, this buffer helps labs achieve more reproducible FISH results—whether working with thin-layer cytology or hematological smears.

Follow the ONCORE Pro® protocol for optimal use. This wash buffer enhances the accuracy and consistency of FISH staining, making it an essential part of any cytogenetic or pathology workflow that requires precise, automated slide preparation.

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