Our MLLT10 probe is designed to detect MLLT10 amplifications and deletions. The probe comes labeled in orange, but can be customized to meet your needs. 

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
MLLT10-20-OR  (Standard Design) 20 (40 μL) 200 μL
MLLT10-20-RE 20 (40 μL) 200 μL
MLLT10-20-AQ 20 (40 μL) 200 μL
MLLT10-20-GR 20 (40 μL) 200 μL
MLLT10-20-GO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a transcription factor and has been identified as a partner gene involved in several chromosomal rearrangements resulting in various leukemias. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010]

Gene Details

Gene Symbol: MLLT10

Gene Name: MLLT10, Histone Lysine Methyltransferase DOT1L Cofactor

Chromosome: CHR10: 21823100-22032559

Locus: 10p12.31

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Mediastinal Myeloid Sarcoma with TP53 Mutation Preceding Acute Myeloid Leukemia with a PICALM-MLLT10 Fusion Gene

This study investigated a case of myeloid sarcoma (MS), a rare tumor often misdiagnosed as malignant lymphoma, that developed into acute myeloid leukemia (AML). Along with pathologic, morphologic, and immunophenotypic characterization, FISH was used to screen for cytogenetic abnormalities. Our MLLT10 helped detect a rare PICALM-MLLT10 fusion in the patient, an abnormality consistent with disease progression to AML.