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ATM 10 test

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

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SKU Test Kits Buffer Dye Color Order Now
ATM-10-OR  (Standard Design) 10 (20 μL) 100 μL

Gene Summary

The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. [provided by RefSeq, Aug 2010]

Gene Details

Gene Symbol: ATM

Gene Name: ATM Serine/threonine Kinase

Chromosome: CHR11: 108093558-108239826

Locus: 11q22.3

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.