COMT FISH Probe
Our COMT probe is designed to detect COMT amplifications and deletions. The probe comes labeled in orange, but can be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| COMT-20-OR (Standard Design) | 20 (40 μL) | 200 μL |
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| COMT-20-RE | 20 (40 μL) | 200 μL |
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| COMT-20-AQ | 20 (40 μL) | 200 μL |
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| COMT-20-GR | 20 (40 μL) | 200 μL |
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| COMT-20-GO | 20 (40 μL) | 200 μL |
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Gene Summary
Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters. [provided by RefSeq, Sep 2008]
Gene Details
Gene Symbol: COMT
Gene Name: Catechol-O-methyltransferase
Chromosome: CHR22: 19929262-19957498
Locus: 22q11.21
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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