PBX1/TCF3 Fusion FISH Probe
Our PBX1/TCF3 fusion probe is designed to detect fusions between PBX1 and TCF3. The probe comes labeled in orange and green, but can be customized to meet your needs.
Gene Background: PBX1-TCF3 fusion is one of the most prevalent rearrangements in B-ALL, occurring in about 6% of adult and childhood patients. The fusion is generated by either the balanced t(1;19)(q23;p13) or the unbalanced der(19)t(1;19)(q23;p13) translocation. Its encoded protein is a transcription factor bearing the transactivation domain of TCF3 and the DNA-binding domain of PBX1, resulting in constitutive activation of PBX1-bound proteins.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
|SKU||Test Kits||Buffer||Dye Color||Order Now|
|PBX1-TCF3-20-ORGR||20 (40 μL)||200 μL|
|PBX1-TCF3-20-GOGR||20 (40 μL)||200 μL|
|PBX1-TCF3-20-REGR||20 (40 μL)||200 μL|
FISH Probe Protocols
|Protocol, Procedure, or Form Name||Last Modified||Download|