YAP1-MAMLD1 Fusion FISH Probe
YAP1 is an oncogene that can help clinicians determine patient prognosis in pediatric ependymoma. Patients with a YAP1 fusion can have a good prognosis compared to those who do not have the fusion. YAP1 has common fusion partners of MAMLD1 and FAM118B and both fusions lead to a better prognosis than individuals with a RELA fusion.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
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YAP1-MAMLD1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
Gene Summary
This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013]
Gene Details
Gene Symbol: YAP1
Gene Name: Yes Associated Protein 1
Chromosome: CHR11: 101981191-102104154
Locus: 11q22.1
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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