CHEK1 FISH Probe
Our CHEK1 probe is designed to detect CHEK1 amplifications and deletions. The probe comes labeled in orange, but can be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CHEK1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |
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| CHEK1-20-RE | 20 (40 μL) | 200 μL |
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| CHEK1-20-AQ | 20 (40 μL) | 200 μL |
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| CHEK1-20-GR | 20 (40 μL) | 200 μL |
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| CHEK1-20-GO | 20 (40 μL) | 200 μL |
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Gene Summary
The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2011]
Gene Details
Gene Symbol: CHEK1
Gene Name: Checkpoint Kinase 1
Chromosome: CHR11: 125495035-125546150
Locus: 11q24.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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