WWOX FISH Probe
The WWOX FISH probe is designed to hybridize to the WWOX gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| WWOX-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| WWOX-20-RE | 20 (40 μL) | 200 μL |  |
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| WWOX-20-GO | 20 (40 μL) | 200 μL |  |
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| WWOX-20-GR | 20 (40 μL) | 200 μL |  |
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| WWOX-20-AQ | 20 (40 μL) | 200 μL |  |
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| WWOX-20-DIG | 20 (40 μL) | 200 μL |  |
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| WWOX-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. This gene spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer. Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12. Disruption of a similar gene in mouse results in impaired steroidogenesis, additionally suggesting a metabolic function for the protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
Gene Details
Gene Symbol: WWOX
Gene Name: WW Domain Containing Oxidoreductase
Chromosome: CHR16: 78133326-79246564
Locus: 16q23.1-q23.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: WWOX FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: WWOX-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping