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TUBA1A FISH Probe

The TUBA1A FISH probe is designed to hybridize to the TUBA1A gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

SKU Test Kits Buffer Dye Color Order Now
TUBA1A-20-OR  (Standard Design) 20 (40 μL) 200 μL
TUBA1A-20-RE 20 (40 μL) 200 μL
TUBA1A-20-GO 20 (40 μL) 200 μL
TUBA1A-20-GR 20 (40 μL) 200 μL
TUBA1A-20-AQ 20 (40 μL) 200 μL
TUBA1A-20-DIG 20 (40 μL) 200 μL
TUBA1A-20-BIO 20 (40 μL) 200 μL

Gene Summary

Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blot studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q. Mutations in this gene cause lissencephaly type 3 (LIS3) - a neurological condition characterized by microcephaly, intellectual disability, and early-onset epilepsy caused by defective neuronal migration. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2017]

Gene Details

Gene Symbol: TUBA1A

Gene Name: Tubulin Alpha 1a

Chromosome: CHR12: 49578582-49582861

Locus: 12q13.12

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Scientific Citations

There are currently no FISH related citations for this gene.

Product Details

Product: TUBA1A FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: TUBA1A-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping