TRMT1 Break Apart FISH Probe
Empire Genomics’ TRMT1 Break Apart FISH Probe is designed to flank the TRMT1 gene and is typically used for detecting TRMT1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TRMT1BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| TRMT1BA-20-AQOR | 20 (40 μL) | 200 μL |
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| TRMT1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| TRMT1BA-20-GORE | 20 (40 μL) | 200 μL |
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| TRMT1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| TRMT1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| TRMT1BA-20-ORGR | 20 (40 μL) | 200 μL |
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| TRMT1BA-20-REGO | 20 (40 μL) | 200 μL |
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| TRMT1BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a tRNA-modifying enzyme that acts as a dimethyltransferase, modifying a single guanine residue at position 26 of the tRNA. The encoded enzyme has both mono- and dimethylase activity when exogenously expressed, and uses S-adenosyl methionine as a methyl donor. The C-terminal region of the encoded protein has both a zinc finger motif, and an arginine/proline-rich region. Mutations in this gene have been implicated in autosomal recessive intellectual disorder (ARID). Alternative splicing results in multiple transcript variants encoding different isoforms. There is a pseudogene of this gene on the X chromosome. [provided by RefSeq, May 2017]
Gene Details
Gene Symbol: TRMT1
Gene Name: TRNA Methyltransferase 1
Chromosome: CHR19: 13215713-13227563
Locus: 19p13.13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: TRMT1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TRMT1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping