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TP53BP1 FISH Probe

The TP53BP1 FISH probe is designed to hybridize to the TP53BP1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

SKU Test Kits Buffer Dye Color Order Now
TP53BP1-20-OR  (Standard Design) 20 (40 μL) 200 μL
TP53BP1-20-OR 20 (40 μL) 200 μL
TP53BP1-20-OR 20 (40 μL) 200 μL
TP53BP1-20-OR 20 (40 μL) 200 μL
TP53BP1-20-OR 20 (40 μL) 200 μL
TP53BP1-20-OR 20 (40 μL) 200 μL
TP53BP1-20-OR 20 (40 μL) 200 μL

Gene Summary

This gene encodes a protein that functions in the DNA double-strand break repair pathway choice, promoting non-homologous end joining (NHEJ) pathways, and limiting homologous recombination. This protein plays multiple roles in the DNA damage response, including promoting checkpoint signaling following DNA damage, acting as a scaffold for recruitment of DNA damage response proteins to damaged chromatin, and promoting NHEJ pathways by limiting end resection following a double-strand break. These roles are also important during V(D)J recombination, class switch recombination and at unprotected telomeres. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2017]

Gene Details

Gene Symbol: TP53BP1

Gene Name: Tumor Protein P53 Binding Protein 1

Chromosome: CHR15: 43699411-43802707

Locus: 15q15.3

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: TP53BP1 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: TP53BP1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping