TGIF1 FISH Probe
The TGIF1 FISH probe is designed to hybridize to the TGIF1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TGIF1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| TGIF1-20-RE | 20 (40 μL) | 200 μL |  |
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| TGIF1-20-GO | 20 (40 μL) | 200 μL |  |
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| TGIF1-20-GR | 20 (40 μL) | 200 μL |  |
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| TGIF1-20-AQ | 20 (40 μL) | 200 μL |  |
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| TGIF1-20-DIG | 20 (40 μL) | 200 μL |  |
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| TGIF1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain. Alternative splicing has been observed at this locus and multiple splice variants encoding distinct isoforms are described. [provided by RefSeq, Jul 2013]
Gene Details
Gene Symbol: TGIF1
Gene Name: TGFB Induced Factor Homeobox 1
Chromosome: CHR18: 3412071-3458406
Locus: 18p11.31
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: TGIF1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TGIF1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping