STRADA FISH Probe
The STRADA FISH probe is designed to hybridize to the STRADA gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| STRADA-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| STRADA-20-RE | 20 (40 μL) | 200 μL |  |
|
| STRADA-20-GO | 20 (40 μL) | 200 μL |  |
|
| STRADA-20-GR | 20 (40 μL) | 200 μL |  |
|
| STRADA-20-AQ | 20 (40 μL) | 200 μL |  |
|
| STRADA-20-DIG | 20 (40 μL) | 200 μL |  |
|
| STRADA-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene contains a STE20-like kinase domain, but lacks several residues that are critical for catalytic activity, so it is termed a 'pseudokinase'. The protein forms a heterotrimeric complex with serine/threonine kinase 11 (STK11, also known as LKB1) and the scaffolding protein calcium binding protein 39 (CAB39, also known as MO25). The protein activates STK11 leading to the phosphorylation of both proteins and excluding STK11 from the nucleus. The protein is necessary for STK11-induced G1 cell cycle arrest. A mutation in this gene has been shown to result in polyhydramnios, megalencephaly, and symptomatic epilepsy (PMSE) syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their full-length nature is not known. [provided by RefSeq, Sep 2009]
Gene Details
Gene Symbol: STRADA
Gene Name: STE20-related Kinase Adaptor Alpha
Chromosome: CHR17: 61780191-61819330
Locus: 17q23.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: STRADA FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: STRADA-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping