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SRC FISH Probe

The SRC FISH probe is designed to hybridize to the SRC gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
SRC-20-OR  (Standard Design) 20 (40 μL) 200 μL
SRC-20-RE 20 (40 μL) 200 μL
SRC-20-GO 20 (40 μL) 200 μL
SRC-20-GR 20 (40 μL) 200 μL
SRC-20-AQ 20 (40 μL) 200 μL
SRC-20-DIG 20 (40 μL) 200 μL
SRC-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: SRC

Gene Name: SRC Proto-oncogene, Non-receptor Tyrosine Kinase

Chromosome: CHR20: 35973087-36033821

Locus: 20q11.23

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Mutational and copy number asset of primary sporadic neuroendocrine tumors of the small intestine

Small intestine neuroendocrine tumors (SI-NETs) are a common type of small-intestine neoplasm. The SRC gene was under analysis to determine a link between aberrations in the gene and SI-NET prognosis. Copy number variations were analyzed with FISH testing. FISH analysis was performed with our SRC gene specific probe along with a chromosome 20 control probe. It was found that gains in SRC gene copy number were associated with a poorer prognosis.

Product Details

Product: SRC FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: SRC-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping