SORBS2 FISH Probe
The SORBS2 FISH probe is designed to hybridize to the SORBS2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SORBS2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SORBS2-20-RE | 20 (40 μL) | 200 μL |  |
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| SORBS2-20-GO | 20 (40 μL) | 200 μL |  |
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| SORBS2-20-GR | 20 (40 μL) | 200 μL |  |
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| SORBS2-20-AQ | 20 (40 μL) | 200 μL |  |
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| SORBS2-20-DIG | 20 (40 μL) | 200 μL |  |
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| SORBS2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases. They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins. This gene encodes the sorbin and SH3 domain containing 2 protein. It has three C-terminal SH3 domains and an N-terminal sorbin homology (SoHo) domain that interacts with lipid raft proteins. The subcellular localization of this protein in epithelial and cardiac muscle cells suggests that it functions as an adapter protein to assemble signaling complexes in stress fibers, and that it is a potential link between Abl family kinases and the actin cytoskeleton. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: SORBS2
Gene Name: Sorbin And SH3 Domain Containing 2
Chromosome: CHR4: 186506597-186877870
Locus: 4q35.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: SORBS2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SORBS2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping