SMARCA4 FISH Probe
The SMARCA4 FISH probe is designed to hybridize to the SMARCA4 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SMARCA4-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SMARCA4-20-RE | 20 (40 μL) | 200 μL |  |
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| SMARCA4-20-GO | 20 (40 μL) | 200 μL |  |
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| SMARCA4-20-GR | 20 (40 μL) | 200 μL |  |
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| SMARCA4-20-AQ | 20 (40 μL) | 200 μL |  |
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| SMARCA4-20-DIG | 20 (40 μL) | 200 μL |  |
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| SMARCA4-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
Gene Details
Gene Symbol: SMARCA4
Gene Name: SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A, Member 4
Chromosome: CHR19: 11071597-11172958
Locus: 19p13.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: SMARCA4 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SMARCA4-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping