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SELENON FISH Probe

The SELENON FISH probe is designed to hybridize to the SELENON gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

SKU Test Kits Buffer Dye Color Order Now
SELENON-20-OR  (Standard Design) 20 (40 μL) 200 μL
SELENON-20-RE 20 (40 μL) 200 μL
SELENON-20-GO 20 (40 μL) 200 μL
SELENON-20-GR 20 (40 μL) 200 μL
SELENON-20-AQ 20 (40 μL) 200 μL
SELENON-20-DIG 20 (40 μL) 200 μL
SELENON-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a glycoprotein that is localized in the endoplasmic reticulum. It plays an important role in cell protection against oxidative stress, and in the regulation of redox-related calcium homeostasis. Mutations in this gene are associated with early onset muscle disorders, referred to as SEPN1-related myopathy. SEPN1-related myopathy consists of 4 autosomal recessive disorders, originally thought to be separate entities: rigid spine muscular dystrophy (RSMD1), the classical form of multiminicore disease, desmin related myopathy with Mallory-body like inclusions, and congenital fiber-type disproportion (CFTD). This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. A second stop-codon redefinition element (SRE) adjacent to the UGA codon has been identified in this gene (PMID:15791204). SRE is a phylogenetically conserved stem-loop structure that stimulates readthrough at the UGA codon, and augments the Sec insertion efficiency by SECIS. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2016]

Gene Details

Gene Symbol: SELENON

Gene Name: Selenoprotein N

Chromosome: CHR1: 25800175-25818221

Locus: 1p36.11

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: SELENON FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: SELENON-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping