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ROCK1 FISH Probe

The ROCK1 FISH probe is designed to hybridize to the ROCK1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ROCK1-20-OR  (Standard Design) 20 (40 μL) 200 μL
ROCK1-20-RE 20 (40 μL) 200 μL
ROCK1-20-GO 20 (40 μL) 200 μL
ROCK1-20-GR 20 (40 μL) 200 μL
ROCK1-20-AQ 20 (40 μL) 200 μL
ROCK1-20-DIG 20 (40 μL) 200 μL
ROCK1-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. A pseudogene, related to this gene, is also located on chromosome 18. [provided by RefSeq, Aug 2015]

Gene Details

Gene Symbol: ROCK1

Gene Name: Rho Associated Coiled-coil Containing Protein Kinase 1

Chromosome: CHR18: 18529702-18691812

Locus: 18q11.1

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: ROCK1 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: ROCK1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping