RFX6 FISH Probe
The RFX6 FISH probe is designed to hybridize to the RFX6 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RFX6-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| RFX6-20-RE | 20 (40 μL) | 200 μL |  |
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| RFX6-20-GO | 20 (40 μL) | 200 μL |  |
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| RFX6-20-GR | 20 (40 μL) | 200 μL |  |
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| RFX6-20-AQ | 20 (40 μL) | 200 μL |  |
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| RFX6-20-DIG | 20 (40 μL) | 200 μL |  |
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| RFX6-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The nuclear protein encoded by this gene is a member of the regulatory factor X (RFX) family of transcription factors. Studies in mice suggest that this gene is specifically required for the differentiation of islet cells for the production of insulin, but not for the differentiation of pancreatic polypeptide-producing cells. It regulates the transcription factors involved in beta-cell maturation and function, thus, restricting the expression of the beta-cell differentiation and specification genes. Mutations in this gene are associated with Mitchell-Riley syndrome, which is characterized by neonatal diabetes with pancreatic hypoplasia, duodenal and jejunal atresia, and gall bladder agenesis.[provided by RefSeq, Sep 2010]
Gene Details
Gene Symbol: RFX6
Gene Name: Regulatory Factor X6
Chromosome: CHR6: 117198375-117253326
Locus: 6q22.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: RFX6 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RFX6-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping