PSMC4 Break Apart FISH Probe
Empire Genomics’ PSMC4 Break Apart FISH Probe is designed to flank the PSMC4 gene and is typically used for detecting PSMC4 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PSMC4BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| PSMC4BA-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| PSMC4BA-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| PSMC4BA-20-GORE | 20 (40 μL) | 200 μL |
|
|
| PSMC4BA-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| PSMC4BA-20-GROR | 20 (40 μL) | 200 μL |
|
|
| PSMC4BA-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| PSMC4BA-20-REGO | 20 (40 μL) | 200 μL |
|
|
| PSMC4BA-20-REGR | 20 (40 μL) | 200 μL |
|
Gene Summary
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the triple-A family of ATPases that is a component of the 19S regulatory subunit and plays a role in 26S proteasome assembly. The encoded protein interacts with gankyrin, a liver oncoprotein, and may also play a role in Parkinson's disease through interactions with synphilin-1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
Gene Details
Gene Symbol: PSMC4
Gene Name: Proteasome 26S Subunit, ATPase 4
Chromosome: CHR19: 40477072-40487353
Locus: 19q13.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: PSMC4 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PSMC4-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping