SEARCH OUR PRODUCT CATALOG

As of July 28th, Empire is operating as an essential New York State business and has no production or shipping delays

PSEN2 FISH Probe

The PSEN2 FISH probe is designed to hybridize to the PSEN2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

SKU Test Kits Buffer Dye Color Order Now
PSEN2-20-OR  (Standard Design) 20 (40 μL) 200 μL
PSEN2-20-RE 20 (40 μL) 200 μL
PSEN2-20-GO 20 (40 μL) 200 μL
PSEN2-20-GR 20 (40 μL) 200 μL
PSEN2-20-AQ 20 (40 μL) 200 μL
PSEN2-20-DIG 20 (40 μL) 200 μL
PSEN2-20-BIO 20 (40 μL) 200 μL

Gene Summary

Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1 or PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor such that, they either directly regulate gamma-secretase activity, or themselves act are protease enzymes. Two alternatively spliced transcript variants encoding different isoforms of PSEN2 have been identified. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: PSEN2

Gene Name: Presenilin 2

Chromosome: CHR1: 227058272-227083804

Locus: 1q42.13

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: PSEN2 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: PSEN2-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping