PSAP Break Apart FISH Probe
Empire Genomics’ PSAP Break Apart FISH Probe is designed to flank the PSAP gene and is typically used for detecting PSAP rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PSAPBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| PSAPBA-20-AQOR | 20 (40 μL) | 200 μL |
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| PSAPBA-20-GOGR | 20 (40 μL) | 200 μL |
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| PSAPBA-20-GORE | 20 (40 μL) | 200 μL |
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| PSAPBA-20-GRGO | 20 (40 μL) | 200 μL |
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| PSAPBA-20-GRRE | 20 (40 μL) | 200 μL |
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| PSAPBA-20-ORGR | 20 (40 μL) | 200 μL |
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| PSAPBA-20-REGO | 20 (40 μL) | 200 μL |
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| PSAPBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
Gene Details
Gene Symbol: PSAP
Gene Name: Prosaposin
Chromosome: CHR10: 73576054-73611082
Locus: 10q22.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PSAP FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PSAP-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping