PRR5 FISH Probe
The PRR5 FISH probe is designed to hybridize to the PRR5 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PRR5-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PRR5-20-RE | 20 (40 μL) | 200 μL |  |
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| PRR5-20-GO | 20 (40 μL) | 200 μL |  |
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| PRR5-20-GR | 20 (40 μL) | 200 μL |  |
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| PRR5-20-AQ | 20 (40 μL) | 200 μL |  |
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| PRR5-20-DIG | 20 (40 μL) | 200 μL |  |
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| PRR5-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a protein with a proline-rich domain. This gene is located in a region of chromosome 22 reported to contain a tumor suppressor gene that may be involved in breast and colorectal tumorigenesis. The protein is a component of the mammalian target of rapamycin complex 2 (mTORC2), and it regulates platelet-derived growth factor (PDGF) receptor beta expression and PDGF signaling to Akt and S6K1. Alternative splicing and the use of alternative promoters results in transcripts encoding different isoforms. Read-through transcripts from this gene into the downstream Rho GTPase activating protein 8 (ARHGAP8) gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene. [provided by RefSeq, Nov 2010]
Gene Details
Gene Symbol: PRR5
Gene Name: Proline Rich 5
Chromosome: CHR22: 45064426-45133561
Locus: 22q13.31
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PRR5 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PRR5-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping