PPL FISH Probe
The PPL FISH probe is designed to hybridize to the PPL gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PPL-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PPL-20-RE | 20 (40 μL) | 200 μL |  |
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| PPL-20-GO | 20 (40 μL) | 200 μL |  |
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| PPL-20-GR | 20 (40 μL) | 200 μL |  |
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| PPL-20-AQ | 20 (40 μL) | 200 μL |  |
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| PPL-20-DIG | 20 (40 μL) | 200 μL |  |
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| PPL-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: PPL
Gene Name: Periplakin
Chromosome: CHR16: 4932507-4987136
Locus: 16p13.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PPL FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PPL-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping