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PHKB FISH Probe

The PHKB FISH probe is designed to hybridize to the PHKB gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
PHKB-20-OR  (Standard Design) 20 (40 μL) 200 μL
PHKB-20-RE 20 (40 μL) 200 μL
PHKB-20-GO 20 (40 μL) 200 μL
PHKB-20-GR 20 (40 μL) 200 μL
PHKB-20-AQ 20 (40 μL) 200 μL
PHKB-20-DIG 20 (40 μL) 200 μL
PHKB-20-BIO 20 (40 μL) 200 μL

Gene Summary

Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The beta subunit is the same in both the muscle and hepatic isoforms, encoded by this gene, which is a member of the phosphorylase b kinase regulatory subunit family. The gamma subunit also includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9B, also known as phosphorylase kinase deficiency of liver and muscle. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. Two pseudogenes have been found on chromosomes 14 and 20, respectively.[provided by RefSeq, Feb 2010]

Gene Details

Gene Symbol: PHKB

Gene Name: Phosphorylase Kinase Regulatory Subunit Beta

Chromosome: CHR16: 47495209-47735434

Locus: 16q12.1

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: PHKB FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: PHKB-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping