OTOP1 FISH Probe
The OTOP1 FISH probe is designed to hybridize to the OTOP1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| OTOP1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| OTOP1-20-RE | 20 (40 μL) | 200 μL |  |
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| OTOP1-20-GO | 20 (40 μL) | 200 μL |  |
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| OTOP1-20-GR | 20 (40 μL) | 200 μL |  |
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| OTOP1-20-AQ | 20 (40 μL) | 200 μL |  |
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| OTOP1-20-DIG | 20 (40 μL) | 200 μL |  |
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| OTOP1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a transmembrane protein which belongs to the otopetrin domain protein family and is required for the formation of otoconia and otoliths, calcium carbonate biominerals within the inner ear of mammals that are required for the detection of linear acceleration and gravity. This gene modulates purinergic control of intracellular calcium in vestibular supporting cells. Naturally occurring mutations in the orthologous mouse gene are associated with nonsyndromic otoconia agenesis and a consequent balance defect. The orthologous mouse gene is also induced in white adipose tissue during obesity. The encoded protein is a component of a counterinflammatory pathway that attenuates obesity-induced adipose tissue inflammation and plays an adaptive role in maintaining metabolic homeostasis in obesity. [provided by RefSeq, Jul 2017]
Gene Details
Gene Symbol: OTOP1
Gene Name: Otopetrin 1
Chromosome: CHR4: 4190529-4228621
Locus: 4p16.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: OTOP1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: OTOP1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping