NOD2 Break Apart FISH Probe
Empire Genomics’ NOD2 Break Apart FISH Probe is designed to flank the NOD2 gene and is typically used for detecting NOD2 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NOD2BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NOD2BA-20-AQOR | 20 (40 μL) | 200 μL |
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| NOD2BA-20-GOGR | 20 (40 μL) | 200 μL |
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| NOD2BA-20-GORE | 20 (40 μL) | 200 μL |
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| NOD2BA-20-GRGO | 20 (40 μL) | 200 μL |
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| NOD2BA-20-GROR | 20 (40 μL) | 200 μL |
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| NOD2BA-20-GRRE | 20 (40 μL) | 200 μL |
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| NOD2BA-20-REGO | 20 (40 μL) | 200 μL |
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| NOD2BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2014]
Gene Details
Gene Symbol: NOD2
Gene Name: Nucleotide Binding Oligomerization Domain Containing 2
Chromosome: CHR16: 50731049-50766987
Locus: 16q12.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: NOD2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NOD2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping