NOD2 FISH Probe
The NOD2 FISH probe is designed to hybridize to the NOD2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
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| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NOD2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| NOD2-20-RE | 20 (40 μL) | 200 μL |  |
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| NOD2-20-GO | 20 (40 μL) | 200 μL |  |
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| NOD2-20-GR | 20 (40 μL) | 200 μL |  |
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| NOD2-20-AQ | 20 (40 μL) | 200 μL |  |
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| NOD2-20-DIG | 20 (40 μL) | 200 μL |  |
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| NOD2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2014]
Gene Details
Gene Symbol: NOD2
Gene Name: Nucleotide Binding Oligomerization Domain Containing 2
Chromosome: CHR16: 50731049-50766987
Locus: 16q12.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: NOD2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NOD2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping