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NLGN3 Break Apart FISH Probe

Empire Genomics’ NLGN3 Break Apart FISH Probe is designed to flank the NLGN3 gene and is typically used for detecting NLGN3 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping
Download Datasheet Download FISH Protocol Download Material Safety Data Sheet

SKU Test Kits Buffer Dye Color Order Now
NLGN3BA-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
NLGN3BA-20-AQOR 20 (40 μL) 200 μL
NLGN3BA-20-GOGR 20 (40 μL) 200 μL
NLGN3BA-20-GORE 20 (40 μL) 200 μL
NLGN3BA-20-GRGO 20 (40 μL) 200 μL
NLGN3BA-20-GROR 20 (40 μL) 200 μL
NLGN3BA-20-GRRE 20 (40 μL) 200 μL
NLGN3BA-20-REGO 20 (40 μL) 200 μL
NLGN3BA-20-REGR 20 (40 μL) 200 μL

Gene Summary

This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. Mutations in this gene may be associated with autism and Asperger syndrome. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Oct 2009]

Gene Details

Gene Symbol: NLGN3

Gene Name: Neuroligin 3

Chromosome: CHRX: 70364680-70391051

Locus: Xq13.1

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

A Hemizygous 370 Kilobase Microduplication at Xq13.1 in a Three-Year-Old Boy With Autism and Speech Delay

Autism is a common developmental disorder that has increased substantially in frequency since the 2000s. Studies have looked into various factors (vitamin deficiencies, viral infections, parental age) as potential causes of the condition, but no clear relationship has been found. In the last decade, studies have started to focus more on possible genetic causes. This study did just that, investigating a duplication on chromosome Xq13.1 in a patient with autism. Empire Genomics’ NLGN3 FISH probe helped to confirm the duplication.
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Product Details

Product: NLGN3 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: NLGN3-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping