NKX2-8 Break Apart FISH Probe
Empire Genomics’ NKX2-8 Break Apart FISH Probe is designed to flank the NKX2-8 gene and is typically used for detecting NKX2-8 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NKX2-8BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| NKX2-8BA-20-AQOR | 20 (40 μL) | 200 μL |
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| NKX2-8BA-20-GOGR | 20 (40 μL) | 200 μL |
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| NKX2-8BA-20-GORE | 20 (40 μL) | 200 μL |
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| NKX2-8BA-20-GRGO | 20 (40 μL) | 200 μL |
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| NKX2-8BA-20-GRRE | 20 (40 μL) | 200 μL |
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| NKX2-8BA-20-ORGR | 20 (40 μL) | 200 μL |
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| NKX2-8BA-20-REGO | 20 (40 μL) | 200 μL |
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| NKX2-8BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects. [provided by RefSeq, Dec 2015]
Gene Details
Gene Symbol: NKX2-8
Gene Name: NK2 Homeobox 8
Chromosome: CHR14: 37049215-37051786
Locus: 14q13.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: NKX2-8 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NKX2-8-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping