NELFA FISH Probe
The NELFA FISH probe is designed to hybridize to the NELFA gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NELFA-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| NELFA-20-RE | 20 (40 μL) | 200 μL |  |
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| NELFA-20-GO | 20 (40 μL) | 200 μL |  |
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| NELFA-20-GR | 20 (40 μL) | 200 μL |  |
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| NELFA-20-AQ | 20 (40 μL) | 200 μL |  |
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| NELFA-20-DIG | 20 (40 μL) | 200 μL |  |
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| NELFA-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: NELFA
Gene Name: Negative Elongation Factor Complex Member A
Chromosome: CHR4: 2009971-1982713
Locus: 4p16.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: NELFA FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NELFA-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping