NALCN Break Apart FISH Probe
Empire Genomics’ NALCN Break Apart FISH Probe is designed to flank the NALCN gene and is typically used for detecting NALCN rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NALCNBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| NALCNBA-20-AQOR | 20 (40 μL) | 200 μL |
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| NALCNBA-20-GOGR | 20 (40 μL) | 200 μL |
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| NALCNBA-20-GORE | 20 (40 μL) | 200 μL |
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| NALCNBA-20-GRGO | 20 (40 μL) | 200 μL |
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| NALCNBA-20-GRRE | 20 (40 μL) | 200 μL |
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| NALCNBA-20-ORGR | 20 (40 μL) | 200 μL |
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| NALCNBA-20-REGO | 20 (40 μL) | 200 μL |
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| NALCNBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a voltage-independent, nonselective cation channel which belongs to a family of voltage-gated sodium and calcium channels that regulates the resting membrane potential and excitability of neurons. This family is expressed throughout the nervous system and conducts a persistent sodium leak current that contributes to tonic neuronal excitability. The encoded protein forms a channelosome complex that includes G-protein-coupled receptors, UNC-79, UNC-80, NCA localization factor-1, and src family tyrosine kinases. Naturally occurring mutations in this gene are associated with infantile neuroaxonal dystrophy, infantile hypotonia with psychomotor retardation and characteristic facies (IHPRF) syndrome, and congenital contractures of the limbs and face with hypotonia and developmental delay (CLIFAHDD) syndrome. A knockout of the orthologous gene in mice results in paralysis with a severely disrupted respiratory rhythm, and lethality within 24 hours after birth. [provided by RefSeq, Apr 2017]
Gene Details
Gene Symbol: NALCN
Gene Name: Sodium Leak Channel, Non-selective
Chromosome: CHR13: 101706129-102068813
Locus: 13q32.3-q33.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: NALCN FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NALCN-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping