MYC Break Apart FISH Probe
Empire Genomics’ MYC Break Apart FISH Probe is designed to flank the MYC gene and is typically used for detecting MYC rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
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MYCBA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL | ||
MYCBA-20-AQOR | 20 (40 μL) | 200 μL | ||
MYCBA-20-GOGR | 20 (40 μL) | 200 μL | ||
MYCBA-20-GORE | 20 (40 μL) | 200 μL | ||
MYCBA-20-GRGO | 20 (40 μL) | 200 μL | ||
MYCBA-20-GROR | 20 (40 μL) | 200 μL | ||
MYCBA-20-GRRE | 20 (40 μL) | 200 μL | ||
MYCBA-20-REGO | 20 (40 μL) | 200 μL | ||
MYCBA-20-REGR | 20 (40 μL) | 200 μL |
Gene Summary
This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]
Gene Details
Gene Symbol: MYC
Gene Name: MYC Proto-oncogene, BHLH Transcription Factor
Chromosome: CHR8: 128748314-128753680
Locus: 8q24.21
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MYC FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MYC-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping