MVK Break Apart FISH Probe
Empire Genomics’ MVK Break Apart FISH Probe is designed to flank the MVK gene and is typically used for detecting MVK rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MVKBA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| MVKBA-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| MVKBA-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| MVKBA-20-GORE | 20 (40 μL) | 200 μL |
|
|
| MVKBA-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| MVKBA-20-GROR | 20 (40 μL) | 200 μL |
|
|
| MVKBA-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| MVKBA-20-REGO | 20 (40 μL) | 200 μL |
|
|
| MVKBA-20-REGR | 20 (40 μL) | 200 μL |
|
Gene Summary
This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Gene Details
Gene Symbol: MVK
Gene Name: Mevalonate Kinase
Chromosome: CHR12: 110011499-110035071
Locus: 12q24.11
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: MVK FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MVK-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping