MMP25 FISH Probe
The MMP25 FISH probe is designed to hybridize to the MMP25 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MMP25-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MMP25-20-RE | 20 (40 μL) | 200 μL |  |
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| MMP25-20-GO | 20 (40 μL) | 200 μL |  |
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| MMP25-20-GR | 20 (40 μL) | 200 μL |  |
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| MMP25-20-AQ | 20 (40 μL) | 200 μL |  |
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| MMP25-20-DIG | 20 (40 μL) | 200 μL |  |
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| MMP25-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, attached to the plasma membrane via a glycosylphosphatidyl inositol anchor. In response to bacterial infection or inflammation, the encoded protein is thought to inactivate alpha-1 proteinase inhibitor, a major tissue protectant against proteolytic enzymes released by activated neutrophils, facilitating the transendothelial migration of neutrophils to inflammatory sites. The encoded protein may also play a role in tumor invasion and metastasis through activation of MMP2. The gene has previously been referred to as MMP20 but has been renamed MMP25. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: MMP25
Gene Name: Matrix Metallopeptidase 25
Chromosome: CHR16: 3096681-3110724
Locus: 16p13.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MMP25 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MMP25-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping