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MERTK FISH Probe

The MERTK FISH probe is designed to hybridize to the MERTK gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping
Download Datasheet Download FISH Protocol Download Material Safety Data Sheet

SKU Test Kits Buffer Dye Color Order Now
MERTK-20-OR  (Standard Design) 20 (40 μL) 200 μL
MERTK-20-RE 20 (40 μL) 200 μL
MERTK-20-GO 20 (40 μL) 200 μL
MERTK-20-GR 20 (40 μL) 200 μL
MERTK-20-AQ 20 (40 μL) 200 μL
MERTK-20-DIG 20 (40 μL) 200 μL
MERTK-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: MERTK

Gene Name: MER Proto-oncogene, Tyrosine Kinase

Chromosome: CHR2: 112656190-112786945

Locus: 2q13

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Genomic Fusions in Pigmented Spindle Cell Nevus of Reed

Pigmented spindle cell nevus (PSCN) of Reed is a type of Spitz nevus that can be difficult to diagnose. It is thought that gene fusions could be the basis of PSCN. The molecular characteristics of PSCN was under study with the use of RNA-sequencing and FISH. FISH analysis was performed with our MERTK and PITX3 fusion probes among other FISH tests. It was found that the majority of PSCN of Reed cases are the result of gene fusions, with the most frequent fusion involving NTRK3.
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Product Details

Product: MERTK FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: MERTK-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping