MDC1 Break Apart FISH Probe
Empire Genomics’ MDC1 Break Apart FISH Probe is designed to flank the MDC1 gene and is typically used for detecting MDC1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MDC1BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| MDC1BA-20-AQOR | 20 (40 μL) | 200 μL |
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| MDC1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| MDC1BA-20-GORE | 20 (40 μL) | 200 μL |
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| MDC1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| MDC1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| MDC1BA-20-ORGR | 20 (40 μL) | 200 μL |
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| MDC1BA-20-REGO | 20 (40 μL) | 200 μL |
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| MDC1BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: MDC1
Gene Name: Mediator Of DNA Damage Checkpoint 1
Chromosome: CHR6_ssto_hap7: 1999890-2017765
Locus: 6p21.33
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: MDC1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MDC1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping