MCM10 Break Apart FISH Probe
Empire Genomics’ MCM10 Break Apart FISH Probe is designed to flank the MCM10 gene and is typically used for detecting MCM10 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MCM10BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| MCM10BA-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| MCM10BA-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| MCM10BA-20-GORE | 20 (40 μL) | 200 μL |
|
|
| MCM10BA-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| MCM10BA-20-GROR | 20 (40 μL) | 200 μL |
|
|
| MCM10BA-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| MCM10BA-20-REGO | 20 (40 μL) | 200 μL |
|
|
| MCM10BA-20-REGR | 20 (40 μL) | 200 μL |
|
Gene Summary
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and it may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein can interact with MCM2 and MCM6, as well as with the origin recognition protein ORC2. It is regulated by proteolysis and phosphorylation in a cell cycle-dependent manner. Studies of a similar protein in Xenopus suggest that the chromatin binding of this protein at the onset of DNA replication is after pre-RC assembly and before origin unwinding. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: MCM10
Gene Name: Minichromosome Maintenance 10 Replication Initiation Factor
Chromosome: CHR10: 13203553-13253104
Locus: 10p13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: MCM10 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MCM10-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping