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MAP2K2 FISH Probe

The MAP2K2 FISH probe is designed to hybridize to the MAP2K2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
MAP2K2-20-OR  (Standard Design) 20 (40 μL) 200 μL
MAP2K2-20-RE 20 (40 μL) 200 μL
MAP2K2-20-GO 20 (40 μL) 200 μL
MAP2K2-20-GR 20 (40 μL) 200 μL
MAP2K2-20-AQ 20 (40 μL) 200 μL
MAP2K2-20-DIG 20 (40 μL) 200 μL
MAP2K2-20-BIO 20 (40 μL) 200 μL

Gene Summary

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, cognitive disability, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: MAP2K2

Gene Name: Mitogen-activated Protein Kinase Kinase 2

Chromosome: CHR19: 4090319-4124126

Locus: 19p13.3

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: MAP2K2 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: MAP2K2-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping