LZTFL1 FISH Probe
The LZTFL1 FISH probe is designed to hybridize to the LZTFL1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LZTFL1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| LZTFL1-20-RE | 20 (40 μL) | 200 μL |  |
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| LZTFL1-20-GO | 20 (40 μL) | 200 μL |  |
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| LZTFL1-20-GR | 20 (40 μL) | 200 μL |  |
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| LZTFL1-20-AQ | 20 (40 μL) | 200 μL |  |
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| LZTFL1-20-DIG | 20 (40 μL) | 200 μL |  |
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| LZTFL1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a ubiquitously expressed protein that localizes to the cytoplasm. This protein interacts with Bardet-Biedl Syndrome (BBS) proteins and, through its interaction with BBS protein complexes, regulates protein trafficking to the ciliary membrane. Nonsense mutations in this gene cause a form of Bardet-Biedl Syndrome; a ciliopathy characterized in part by polydactyly, obesity, cognitive impairment, hypogonadism, and kidney failure. This gene may also function as a tumor suppressor; possibly by interacting with E-cadherin and the actin cytoskeleton and thereby regulating the transition of epithelial cells to mesenchymal cells. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2013]
Gene Details
Gene Symbol: LZTFL1
Gene Name: Leucine Zipper Transcription Factor Like 1
Chromosome: CHR3: 45865445-45883621
Locus: 3p21.31
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: LZTFL1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: LZTFL1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping