LRRFIP2 FISH Probe
The LRRFIP2 FISH probe is designed to hybridize to the LRRFIP2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LRRFIP2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| LRRFIP2-20-RE | 20 (40 μL) | 200 μL |  |
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| LRRFIP2-20-GO | 20 (40 μL) | 200 μL |  |
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| LRRFIP2-20-GR | 20 (40 μL) | 200 μL |  |
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| LRRFIP2-20-AQ | 20 (40 μL) | 200 μL |  |
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| LRRFIP2-20-DIG | 20 (40 μL) | 200 μL |  |
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| LRRFIP2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene, along with MYD88, binds to the cytosolic tail of toll-like receptor 4 (TLR4), which results in activation of nuclear factor kappa B signaling. The ubiquitin-like protein FAT10 prevents the interaction of the encoded protein and TLR4, thereby inactivating the nuclear factor kappa B signaling pathway. In addition, this protein can downregulate the NLRP3 inflammasome by recruiting the caspase-1 inhibitor Flightless-I to the inflammasome complex. [provided by RefSeq, Jan 2017]
Gene Details
Gene Symbol: LRRFIP2
Gene Name: LRR Binding FLII Interacting Protein 2
Chromosome: CHR3: 37094116-37217851
Locus: 3p22.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: LRRFIP2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: LRRFIP2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping