LGMN Break Apart FISH Probe
Empire Genomics’ LGMN Break Apart FISH Probe is designed to flank the LGMN gene and is typically used for detecting LGMN rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LGMNBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| LGMNBA-20-AQOR | 20 (40 μL) | 200 μL |
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| LGMNBA-20-GOGR | 20 (40 μL) | 200 μL |
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| LGMNBA-20-GORE | 20 (40 μL) | 200 μL |
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| LGMNBA-20-GRGO | 20 (40 μL) | 200 μL |
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| LGMNBA-20-GRRE | 20 (40 μL) | 200 μL |
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| LGMNBA-20-ORGR | 20 (40 μL) | 200 μL |
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| LGMNBA-20-REGO | 20 (40 μL) | 200 μL |
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| LGMNBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined. These two variants encode the same isoform. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: LGMN
Gene Name: Legumain
Chromosome: CHR14: 93170151-93215047
Locus: 14q32.12
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: LGMN FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: LGMN-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping